Hyaluronic acid
What is hyaluronic acid?
Hyaluronic acid is a substance naturally produced by the body, but it diminishes with age. In aesthetic medicine, it is used in anti-aging treatments because it can hold up to 200 times its weight in water, contributing to skin rejuvenation through its hydrating and moisturizing properties, among other benefits.
It can be used in two formulations:
Non-crosslinked hyaluronic acid: in its simplest, diluted form, it helps to hydrate the skin.
Crosslinked hyaluronic acid: used to shape or add volume to facial features that diminish over time.

What is hyaluronic acid used for?
Given its benefits, it can be used to improve skin quality and address signs of aging on the face, as follows:
- In the lower third of the face, hyaluronic acid is indicated as a filler for pronounced wrinkles, such as the nasolabial folds (the triangular area around the lips) and the corners of the mouth.
- It can be used preventively in areas prone to future sagging on the face.
- It is also ideal for lip augmentation when there is a natural loss of volume.
- Cheek augmentation and jawline contouring.
- Although dark circles have various causes, hyaluronic acid is ideal for under-eye filling, addressing one of the signs most commonly associated with fatigue and aging.
Benefits
The effects of hyaluronic acid are highly effective and fast for smoothing deep wrinkles or restoring volume in facial areas that have lost it due to aging. Other benefits include:
- Moisturizes and hydrates, helping to eliminate skin dryness.
- Improves skin tone and texture by promoting a firmer appearance.
- Stimulates cell regeneration by repairing damaged skin.
- Enhances radiance by evening out skin tone.
Duration
It is a substance that is gradually absorbed over a period of 6 to 18 months, at which point reapplication may be necessary.
Application Process
Hyaluronic acid is administered through injections after the skin is cleansed and the target areas are marked during the assessment.
Expectations
Hyaluronic acid is one of the most widely used substances in aesthetic medicine due to its broad applications in facial rejuvenation procedures and its satisfactory results. Its effects are visible for 6 to 18 months, with mild side effects and a wide safety margin.

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Frequently Asked Questions
Is a sensitivity test necessary before using it?
No. Allergic reactions to hyaluronic acid are extremely rare.
How long do the treatment results last?
Between 6 and 18 months.
How many sessions are necessary?
The duration will depend on the medical diagnosis, the patient’s skin, and the expectations established.
How many years does hyaluronic acid reverse or “rejuvenate”?
It is not about “reversing” a specific number of years like a mathematical formula. However, its effects are immediate upon application, significantly reducing deep wrinkles, improving skin appearance, and filling areas of the face that have lost volume over time. Results can last between 6 and 18 months.
What are the contraindications of hyaluronic acid?
Although it is a very safe product, moderation by the patient is crucial, as some people believe that using more product will yield better results. On the contrary, this increases the risk of product accumulation or unnatural effects. It should not be used in pregnant or breastfeeding women, individuals with skin infections, or those on anticoagulants.
Contraindications
Hyaluronic acid is not used in pregnant or breastfeeding women. It is also contraindicated in individuals with active skin infections or bleeding disorders.
Possible side effects include swelling or redness at the injection site, which typically subsides within a few hours. However, if pain persists and is not relieved by medication, it is important to consult a physician, as complications may arise from incorrect application or dosing. Although uncommon, the following effects may occur:
Unnatural appearance: occurs when an excessive amount of product is applied. It is commonly noticeable in the cheeks or lips.
Edema or swelling: may occur around the eyes or lips, sometimes presenting a dark or purplish hue.
Asymmetry: irregular facial shape.
Temporary vision loss: known as amaurosis, this can occur if hyaluronic acid is inadvertently injected into the ophthalmic artery and migrates to that area.
Deep and dark under-eye circles: occur due to excessive pressure in the area, which affects blood vessels and causes the dark coloration.
The way to counteract these effects is through the application of hyaluronidase, an enzyme that rapidly breaks down hyaluronic acid. Medical supervision of the area is required.
Recommendations
Hyaluronic acid used in aesthetic medicine treatments should meet the following characteristics:
- It should not migrate within the tissues or into vascularized areas.
- It should not cause allergic reactions.
- It should not be permanent. The substance is gradually absorbed over a period of 6 to 18 months.
Since skin appearance and chronological age depend on multiple factors, it is important that, in addition to hyaluronic acid treatments, patients maintain a lifestyle that helps slow down skin aging through practices such as:
- A diet rich in vegetables.
- A diet that minimizes dairy, gluten, and empty-calorie foods.
- Daily sun protection (80% of aging effects are influenced by sun exposure).
- Exercise, at least 90 minutes per week.
- Stress management techniques.
References
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