Mesopeeling
What is Mesopeeling?
Mesopeel is an aesthetic medicine procedure that combines two powerful techniques to counteract skin deterioration: peeling and mesotherapy. An exfoliating agent is applied to remove superficial lesions, followed by tissue regeneration. Afterwards, mesotherapy is used to deliver substances that stimulate skin tone, radiance and overall vitality.

What is it for?
Mesopeel is ideal for those looking to treat skin concerns such as acne, dark spots, stretch marks, photoaging, dullness and more, as well as to restore the qualities of healthy and youthful skin. The removal of dead skin cells helps recover the brightness and youthfulness of the face, neck, décolleté and hands. Additionally, the technique can be used anywhere on the body to address stretch marks, cellulite or skin laxity.
Benefits
One of the main benefits of mesopeel is that it is painless, non-invasive and does not interfere with the patient’s social life, as it is a gentle peel. With mesotherapy, specific concerns can be treated directly to improve the appearance of the skin. This allows benefits such as:
- Stimulating collagen production.
- Treating skin laxity.
- Treating tissue irregularities and certain dark spots.
- Eliminating fine lines.
- Treating stretch marks and scars.
- Reducing the appearance of cellulite.
- Restoring elasticity.
For the mesopeel technique, agents such as Melanostop Tranex (commercially known as mesopeel® melanostop tran3x), Mesopeel TCA, Mesopeel Azelan and Mesopeel Pyruvic are commonly used. Their effects range from accelerating skin renewal to remove accumulated melanin, to helping restore radiance and promote skin rejuvenation.
Duration
The session may last around 30 minutes. According to Dr. Juan Carlos Lloreda, specialist in aesthetic and anti-aging medicine, although the number of sessions depends on each patient’s concerns, a minimum of three sessions is recommended to see results.
Results can last between 6 months and one year. This depends on patient care such as sun protection, as well as a lifestyle that includes proper daily facial cleansing, a healthy diet and regular physical activity.
Application process
- The first step is a deep cleansing of the skin.
- Then the selected peeling agent is applied.
- The next step is to apply, through mesotherapy, the active substances that work directly on the area that needs to be treated.
- The session ends with soothing products that hydrate and protect the skin.
Expectations
Exfoliating agents have demonstrated excellent clinical efficacy according to medical research. This type of exfoliation has grown in popularity among patients due to its results and minimal side effects. Mesopeel delivers progressive improvements as the treatment advances. Patients can expect smoother skin with a natural glow, a more even tone, reduced dark spots and an improvement in the appearance of scars.
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Frequently Asked Questions
Does mesopeeling hurt?
It does not cause pain. Side effects may include itching, burning or peeling, which subside quickly.
How many sessions are needed?
The specialist will determine the number of sessions needed for each patient after the initial evaluation.
How effective is mesopeeling?
It is a highly effective technique in aesthetic medicine to counteract the effects of aging and skin irregularities, such as dark spots or photoaging.
Contraindications
Mesopeeling is not recommended for individuals with skin conditions such as allergies, infections or wounds. These treatments are also not performed on pregnant or breastfeeding women.
Side effects
Patients may experience redness, skin sensitivity or peeling, which resolve quickly.
References
Fabbrocini, G., De Vita, V., Pastore, F., Panariello, L., Fardella, N., Sepulveres, R., Monfrecola, G. (2014). “Chemical peeling: science and techniques for the use of chemical peels in dermatology.” Dermatologic Therapy, 27(6), 327-337.
Sarkar, R., Arora, P., Garg, V. K. (2017). “Cosmeceuticals for hyperpigmentation: What is available?” Journal of Cutaneous and Aesthetic Surgery, 10(1), 3-10.
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