Exosomes
What are exosomes?
Exosomes are cellular messengers. They are microvesicles derived from stem cells or plant-based sources that carry information between cells to enhance or activate their functions. In aesthetic medicine, they are used to promote tissue regeneration and rejuvenation.

They are formulated with a base of non-crosslinked hyaluronic acid and contain proteins and lipids with reparative, regenerative, and anti-inflammatory properties. Results are superior compared to other treatments such as Platelet-Rich Plasma (PRP).
What are exosomes used for?
The primary function of exosomes is to repair and revitalize tissues affected by aging. At Dr. Juan Carlos Lloreda’s Aesthetic and Anti-Aging Medicine Center, this technology is used to treat concerns such as melasma, acne, rosacea, enlarged pores, and atopic dermatitis. It is also applied in procedures designed to reduce wrinkles and improve skin quality on the face, neck, décolleté, and hands.
They are also effective for treating scars, including those caused by acne. In aesthetic medicine, they are used to support hair strengthening and help counteract hair loss.
Before becoming part of aesthetic medicine, this technology originated in the field of tissue regeneration for the treatment of neurological, autoimmune, and vascular diseases, as well as tumor management, among others.
Benefits
One of the major advantages of exosomes is for patients who prefer to avoid needles or cannulas. Their application can be performed using technologies such as LaseMD and Fractional CO2 Laser, which create microchannels in the skin without causing damage. The product is then applied so it can penetrate directly to the targeted area. This technique, known as drug delivery, enables active ingredients to reach the deeper layers of the skin for enhanced absorption and more precise results.
This technology promotes tissue regeneration by facilitating communication between cells. Results outperform other treatments intended to help counteract the effects of photoaging, chronological aging, and environmental pollution. It also addresses a wide range of dermatological conditions that can be effectively treated.
Its application gives the skin a natural radiance, reduces redness, evens out tone, and overall provides a healthier and more youthful appearance.
Duration
Results can remain visible for up to six months after treatment.
Application process
Dr. Juan Carlos Lloreda explains that in his clinic LaseMD is used to create microchannels in the skin without causing injury. The product is then applied, eliminating the need for needles during the procedure. This allows the active components to reach the epidermis and dermis, where fibroblasts are stimulated to produce collagen and elastin.
However, the treatment can also be performed through mesotherapy, a technique that uses micro-needles to deliver small doses of the product precisely to the targeted area. Additional options include intradermal application or, as performed at Dr. Juan Carlos Lloreda’s Medical Center, drug delivery. This technique allows for the precise administration of exosomes through controlled microchannels in the skin for deep and effective absorption.
Expectations
Exosomes are a safe and regenerative treatment option. Results depend on the patient’s baseline skin condition and may begin to appear within two to three days after application. Patients typically notice smoother skin, a healthy and natural glow, reduced wrinkles, and an even skin tone with improved texture.
With their regenerative and anti-inflammatory properties, this technology can also be used to treat complex dermatological conditions such as psoriasis, among others.

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Frequently Asked Questions
How soon are results visible with exosomes?
Two to three days after application. Results may remain visible for up to six months, depending on the recommended treatment and the patient’s skin condition.
Do exosomes help extend the hair growth cycle?
Essentially, this technology supports the regeneration of hair follicle cells as part of a revitalizing treatment that helps reduce hair loss while strengthening and thickening the hair.
Is there any downtime or specific aftercare required following the treatment?
Although the treatment does not require downtime, it is recommended to avoid intense physical exercise and activities in humid environments to prevent increased redness, bruising, or other discomfort.
What are exosomes and what are they used for?
They act as messengers that transmit information between cells to stimulate regeneration in tissues affected by aging or skin conditions that have diminished overall skin quality.
Contraindications
It is not recommended for women who are pregnant or breastfeeding, or for patients with active skin infections or severe skin allergies.
Regarding possible side effects, there are no significant cases reported for this procedure. However, if the molecule is combined with hyaluronic acid, there is a small possibility of complications such as nodule formation.
Recommendations
After treatment, it is recommended to avoid intense physical activity and humid environments in order to prevent increased redness, bruising, or other discomfort.
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